The Indian Council of Medical Research has launched the ‘Malaria Elimination Research Alliance (MERA) India’ to eliminate malaria from India by 2030. The initiative is a conglomeration of partners working on malaria control. The principal activity of the alliance is to prioritise, plan, conduct, scale up and translate relevant research in a coordinated and combinatorial way in order to have a tangible impact of this research on the population at risk for malaria. The MERA India does not intend to duplicate international efforts rather complement this on a national scale while contributing to the broader global agenda. The alliance will facilitate trans-institutional coordination and collaboration around a shared research agenda which responds not only to programmatic challenges and addresses gaps in available tools but also pro actively contributes to targeted research. It aims to harness and reinforce research in coordinated and combinatorial ways in order to achieve tangible impact on malaria elimination.